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Hyun Guy KANG

Name
Hyun Guy KANG, M.D., Ph.D.(adjunct professor)
Faculty Appointment
(title, department)
professor, Department of Cancer Biomedical Science, NCC-GCSP
Area of Expertise


Musculoskeletal tumor
Sarcoma
Bone metastasis
E-mail
ostumor@ncc.re.kr
Work Experience
bachelor's degree (MD) Chonbuk National University Medicine 1994
Master´s degree Chonbuk National University Orthopedics 1998
Doctor´s degree Chonbuk National University Orthopedics 2001
Educational Background
2005.03 ~ 2006.02 Orthopedic Oncology Seoul National University Hospital Fellow
2006.04 ~ now Orthopedic Oncology Clinic National Cancer Center Staff Surgeon
2010.04 ~ 2011.03 MD Anderson Cancer Center Postdoctoral fellow
2015 Specific Organs Cancer Branch National Cancer Center NCC Research Institute Associate Researcher
2016 Department of System Cancer Science, NCC-GCSP Associate professor,
Research Interests (Please place in paragraph form)
Medical engineering innovation
Metastatic bone tumor
Sarcoma
International Collaboration
Achievements
2022 SCI-E Evaluation of Intraosseous Pressure during Pelvic Percutaneous Cement Injection: An In Vitro Study in Swine: CLINICS IN ORTHOPEDIC SURGERY. 14:e56~ (2.503)

2022 SCI-E Clinical characteristics and long?term outcomes of rhabdomyosarcoma in Korean children, adolescents and young adults: a single?center experience: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. Online:Published (4.322)

2021 SCI-E Osteosarcoma in Adolescents and Young Adults: CELLS. 10(10):2684~ (6.6)

2021 SCI-E Percutaneous Cementoplasty for the Pelvis in Bone Metastasis: 12-Year Experience: ANNALS OF SURGICAL ONCOLOGY. 29(2):1413~1422 (5.344)

2021 SCI-E Incidence Patterns and Outcomes of Ewing Sarcoma in South Korea (1999-2017): A Retrospective Analysis Using Korea Central Cancer Registry Data: CANCER RESEARCH AND TREATMENT. Online:Published (4.679)

2021 SCI-E In vivo analysis of post-joint-preserving surgery fracture of 3D-printed Ti-6Al-4V implant to treat bone cancer: BIO-DESIGN AND MANUFACTURING. 4(4):879~888 (6.302)

2021 SCI-E Vincristine, Irinotecan, and Temozolomide as a Salvage Regimen for Relapsed or Refractory Sarcoma in Children and Young Adults: CANCER RESEARCH AND TREATMENT. Online:Published (4.679)

2021 SCI-E 3D-Printed Connector for Revision Limb Salvage Surgery in Long Bones Previously Using Customized Implants: METALS. 11(5):707~ (2.351)

2020 SCI-E A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression. Nature Communications: NATURE COMMUNICATIONS. 11(1):5023~ (12.121)

2020 SCI-E New 3-dimensional implant application as an alternative to allograft in limb salvage surgery: a technical note on 10 cases (letter): ACTA ORTHOPAEDICA. 91(5):617~619 (2.965)

2020 SCI-E New 3-dimensional implant application as an alternative to allograft in limb salvage surgery: a technical note on 10 cases: ACTA ORTHOPAEDICA. :1~8 (2.965)

2020 SCI-E Targeting TJP1 attenuates cell-cell aggregation and modulates chemosensitivity against doxorubicin in leiomyosarcoma: JOURNAL OF MOLECULAR MEDICINE-JMM. 98(5):761~773 (4.427)

2020 SCI-E The application of 3D-printing technology in pelvic bone tumor surgery: JOURNAL OF ORTHOPAEDIC SCIENCE. Online:Published (1.259)

2020 SCI-E Integration of a Three-Dimensional-Printed Titanium Implant in Human Tissues: Case Study: APPLIED SCIENCES-BASEL. 10(2):553~ (2.474)

2019 SCI Histologic Response and Toxicity following Interval-Compressed Four-Drug Therapy Given Preoperatively in Children and Young Adults with Osteosarcoma: A Retrospective Study: ONCOLOGY. Online:Published (2.278)

2019 SCI-E Histological findings of regeneration in retrieved pasteurized bone grafts: Journal of Orthopaedic Science. 24(4):737~741 (1.257)

2019 SCI Upregulation of transforming growth factor-beta type I receptor by interferon consensus sequence-binding protein in osteosarcoma cells: Biochimica et Biophysica Acta(BBA)-Molecular Cell Research. 1866(5):761~772 (4.739)

2019 SCI-E Biomechanical Evaluation of a New Fixation Type in 3D-Printed Periacetabular Implants using a Finite Element Simulation: Applied Sciences-Basel. 9(5):820~820 (2.217)

2018 SCI Preliminary results: use of multi-hole injection nails for intramedullary nailing with simultaneous bone cement injection in long-bone metastasis: Skeletal radiology. 48(2):219~225 (1.567)

2018 SCI-E Integrated molecularcharacterization of adult soft tissue sarcoma fortherapeutic targets: BMC medical genetics. 19(supple1):216~216 (1.913)

2018 SCI Transcriptome and protein interaction profiling in cancer cells with mutations in histone H3.3: SCIENTIFIC DATA. 5:10283~10283 (5.311)

2018 기타 3차원 프린팅 기술과 이를 활용한 골종양 수술: The Journal of the Korean Orthopaedic Association. 53(6):466~477 (0)

2018 SCI-E Bone tumor resection guide using three­dimensional printing for limb salvage surgery: Journal of surgical oncology. 51(8):373~377 (2.886)

2018 기타 3D-Printed Personalized Titanium Implant Design,Manufacturing and Verification for Bone Tumor Surgery of Forearm: Biomedical Journal of Scientific & Technical Research. 10(3):1~6 (0)

2018 기타 Three-Dimensionally Printed Personalized Implant Design and Reconstructive Surgery for a Bone Tumor of the Calcaneus: JBJS case connector. 8(2):e25~e25 (0)

2018 SCI-E Joint-preserving palliative surgery using self-locking screws of intramedullary nail and percutaneous cementoplasty for proximal humeral metastasis in the advanced cancer patients: World journal of surgical oncology. 16(1):93~93 (1.792)

2017 SCI The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing: Scientific reports. 7(1):13459~13459 (4.259)

2017 SCI Percutaneous Palliative Surgery for Femoral Neck Metastasis Using Hollow Perforated Screw Fixation and Bone Cement: The Journal of Bone & Joint Surgery. 2(2):e0018~e0018 (4.8)

2017 SCI-E Percutaneous cementoplasty for acetabulum in patients with bone metastasis: Acta Orthopaedica Belgica. 83:480~487 (0.576)

2016 기타 Minimal Invasive Surgery of Metastatic Bone Tumor: InTech. 7:127~141 ()

2016 기타 Osteoarticular Repair with Bone Cement for Advanced Pigmented Villonodular Synovitis of the Hip; A Temporizing and Yet Durable Reconstruction: Open J Clin Med Case Rep. 2 Issue 13:1135:1~7 ()

2016 SCI Closed intramedullary nailing with percutaneous cement augmentation for long bone metastases: The Bone and Joint Journal. 98-B(5):703~709 (2.66)

2016 기타 Development of a Measurement System of the Transferred Pressure from Intermittent Pneumatic Compression Device: Journal of Biomedical Engineering Research. 37:39~45 ()

2016 SCI Investigation of Blood Flow During Intermittent Pneumatic Compression and Proposal of a New Compression Protocol: Clinical and Applied Thrombosis/Hemostasis. Online:Published (1.973)

2015 SCI-E Minimally invasive surgery for femoral neck fractures using bone cement infusible hollow-perforated screw in high-risk patients with advanced cancer.: Surgical Oncology. 24(3):226~231 (3.27)

2015 기타 Diagnoses and Approaches of Soft Tissue Tumors for Orthopaedic Non-Oncologists: Journal of the Korean orthopaedic association. 50:269~279 (0)

2015 기타 Distinct Clinical Characteristics of Unplanned Excision in Synovial Sarcoma.: Clinics in Orthopedic Surgery. 7(2):254~60 (0)

2015 SCI-E Development of Biopsy Gun for Aspiration and Drug Injection.: Sugical Innovation. 22(2):163~170 (1.458)

2014 SCI-E Palliative percutaneous stabilization of lower extremity for bone metastasis using flexible nails and bone cement: Surgical oncology. 23(4):192~198 (2.367)

2014 기타 Low Grade Chondrosarcoma Presenting as Progressive Valgus Limb Deformity in a Growing Period: The Journal of the Korean Bone and Joint Tumor Society. 20:41~45 (0)

2014 기타 Limb salvage surgery using whole knee joint allograft reconstruction in osteosarcoma: Journal of the Korean Orthopaedic Association. 49:244~249 (0)

2014 SCI-E Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells: Cell death & disease. 5:e1224~e1224 (5.177)

2014 SCI-E Percutaneous navigation surgery of osteoid osteoma of the femur neck: Minimally Invasive Therapy & Allied Technologies. 23(1):58~62 (1.18)

2013 SCI-E Clinical outcome prediction of percutaneous cementoplasty for metastatic bone tumor using 18F-FDG PET-CT: Annals of nuclear medicine. 27(10):916~923 (1.41)

2013 기타 Radiofrequency ablation for the treatment of recurring desmoid tumors following repeated surgical resection: usefulness of the moving tip technique: Current Orthopaedic Practice. 24:547~551 ()

2013 기타 Intercalary allograft reconstruction after malignant tumor resection around the knee: Journal of the Korean Orthopaedic Association. 48(1):9~15 (0)

2012 SCI-E Gait Symmetry Analysis Protocol for Whole Leg Movement Symmetry Evaluation: Journal of Machanics in Medicine and Biology. 12(4):1~14 (0.468)

2012 SCI Prediction of tumour necrosis fractions using metabolic and volumetric 18F-FDG PET/CT indices, after one course and at the completion of neoadjuvant chemotherapy, in children and young adults with osteosarcoma: European Journal of Nuclear Medicine and Molecular Imaging. 39(1):39~49 (4.991)

2011 SCI-E Minimally invasive surgery of humeral metastasis using flexible nails and cement in high-risk patients with advanced cancer.: Surgical Oncology. 20:32~37 (2.886)

2011 SCI Does delayed reexcision affect outcome after unplanned excision for soft tissue sarcoma?: Clinical Orthopaedics and Related Research. 469(3):877~883 (2.116)

2011 기타 Soft tissue reconstruction of the foot using the distally based island pedicle flap after resection of malignant melanoma.: Clinics in orthopedic surgery.. 2(4):244~249 ()

2010 SCI Resection of a physeal bar under computer-assisted guidance.: Journal of bone and joint surgery British Volume. 92(10):1452~1455 (2.655)

2010 SCI MRI-guided Navigation Surgery With Temporary Implantable Bone Markers in Limb Salvage for Sarcoma: Clinical Orthopaedics and Related Research (CORR). 468(8):2211~2217 (2.065)

2010 기타 3D Gait Analysis of Limb Salvage Patients with Osteoarticular knee allograft reconstruction: J. Biomed. Eng. Res/의공학회지. 31:74~80 ()

2010 SCI-E Desmoplastic fibroma with malignant transformation.: Annals of diagnostic pathology. 14(1):50~55 (1.128)

2010 SCI-E Proton magnetic resonance spectroscopy of musculoskeletal lesions at 3 T with metabolite quantification: Clinical Imaging. 34/(1):47~52 (0.725)

2009 SCI The treatment of metastasis to the femoral neck using percutaneous hollow perforated screws with cement augmentation.: J Bone Joint Surg Br.. 91(8):1078~1082 (2.196)

2008 기타 concurrent liposarcoma and fat necrosis in an encapsulated mass: report of a case: J. of Korean Bone & Joint Tumor Soc.. 14-2:187~191 ()

2008 SCI Metal Artifact Reduction by the Alteration of Technical Factors in Multidetector Computed Tomography: A 3-Dimensional Quantitative Assessment: Journal of computer assisted tomography. 32(4):630~633 (1.53)

2008 SCI Computer-assisted sacral tumor resection: The Journal of Bone and Joint Surgery (American). 90:1561~1566 (2.487)

2007 SCI RECK expression in osteosarcoma: correlation with matrix metalloproteinases activation and tumor invasiveness.: Journal of Orthopaedic Research(상위20#이내 학술지임). 25:696~702 (2.784)

2007 기타 Low-heat Treated Intercalary Autograft Reconstruction in Limb Salvage of Primary Malignant Bone Tumor: J Korean Orthop Assoc. 42:291~297 ()

2007 SCI Unicameral Bone Cysts: A comparison of autologous bone marrow grafting with steroid injection: J Bone Joint Surg (Br). 89(2):222~226 (1.79)

2007 SCI Unicameral bone cysts: a comparison of injection of steroid and grafting with autologous bone marrow: Journal of Bone and Joint Surgery - British volume. 89:222~226 (1.79)

2006 기타 Elastofibroma Scapulae: J Korean Bone & Joint Tumor. 12:118~125 ()

2006 기타 Reconstruction with Replantation of the Resected Bone after Low Heat Treatment for Malignant Pelvic Bone Tumors: J Korean Orthop Assoc. 41:519~526 ()

2006 기타 Temporary Use of External Fixators for Soft Tissue Lengthening in the Treatment of Complications after Limb Salvage Surgery: J Korean Bone & Joint Tumor Soc. 11:134~140 ()

2005 기타 Integrin αVβ3, α5β1 Effects on Cell Proliferation and Migration in Human Osteosarcoma: J Orthop Research. 8:130~136 ()

2005 기타 Expressions of Apoptotic Genes (survivin, bcl-2, bax) and Clinical Relevance in Osteosarcoma: J Korean Bone & Joint Tumor Soc. 11:118~125 ()

2005 기타 Analysis of RECK (a novel MMP inhibitor) Expression and its Roles as a Biomarker and Evaluation of RECK as a Potential Therapeutic Agent for Osteosarcoma: J Orthop Research. 8:121~129 ()

2005 기타 Prosthetic Survival and Functional Evaluation in Prosthetic Reconstruction of Malignant Bone Tumors of the Proximal Tibia: Korean Orthop Assoc. 40:749~756 ()