- Anders Lindroth, Ph.D.(full-time professor)
- Faculty Appointment
- Associate Professor, Department of Cancer Biomedical Science, NCC-GCSP
- Area of Expertise
- Cancer Genetics and Epigenomics
- Work Experience
- Researcher, DKFZ – German Cancer Research Center, Heidelberg, Germany (2011-2014)
Adjunct Lecturer, Animal Breeding and Genetics, SLU – Swedish University of Agricultural Sciences, Uppsala, Sweden (2009-2010)
Research Associate, Department of Molecular Biology and Microbiology, Uppsala University, Uppsala, Sweden (2008)
Postdoctoral Research Associate, Cornell University, Nutritional Sciences, Ithaca, USA (2004-2008)
Postdoctoral Researcher, Molecular, Cell & Developmental Biology, UCLA - University of California, Los Angeles, USA (2000-2004)
- Educational Background
- Ph.D., SLU - Swedish University of Agricultural Sciences (2000)
B.Sc., Uppsala University, Uppsala, Sweden
- Research Interests (Please place in paragraph form)
- Our research focus on tumor-related epigenetic dysregulation, both as active and passive contributor of tumorigenesis. Since epigenetic modifications in large part serve the purpose of fine-tuning transcriptional processes, protect the genome, anchor the chromosomal regions to various compartments of the nucleus, and to locally and globally orchestrate coordinated gene expressions by modifying critical control elements of the genome, we strive to analyse individual epigenetic regulators in an as simple cytogenetic background as possible to reduce noice. Our study objects are therefore childhood tumors that provide the inner and most aggressive workings of neoplastic growth.
The goal of our research is to unravel epigenetic patterns that drive tumorigenesis and can be used as biomarkers in prevention and stratification of patients in the clinic.
Students interested in epigenetics and bioinformatics in all its aspects from model organisms to cancer are welcome to apply to our research group.
- International Collaboration
- Epigenomics of histone mutations in glioblastoma and giant cell tumor of the bone, with Prof. Dr. Christoph Plass and Prof. Dr. Stefan Pfister – German Cancer Research Center, Heidelberg (2014 - present).
Histone methylation affecting tumorigenesis in colorectal cancers, with Dr. Tobias Sjöblom – Rudbeck laboratory, Uppsala University, Sweden (2015 – present).