교수진 소개
- Name
- Joonha KWON, Ph.D.
- Faculty Appointment
(title, department)
- Assistant Professor, Department of Cancer AI & Digital Health, NCC-GCSP, NCC
Senior Researcher, Bioinformatics Branch, Division of Cancer Data Science, Research Institute, NCC
- Area of Expertise
- Bioinformatics, Computational Biology, Artificial Intelligence, Genomics, Oncology, Immunology, Immunotherapy
- Contact no
- 031-920-2583
- E-mail
- Joon2k@ncc.re.kr
- Work Experience
- Aug 2023 – : Senior Researcher, Bioinformatics Branch, Division of Cancer Data Science, Research Institute, National Cancer Center
Sep 2022 - July 2023 : Postdoctoral Research Fellow, Department of Bio and Brain Engineering, KAIST
Jan 2017 - Aug 2017 : Research Associate, Department of Bio and Brain Engineering, KAIST
- Educational Background
- Sep 2017 - Aug 2022 : Ph.D., Bio and Brain Engineering, KAIST
Sep 2013 - Feb 2017 : M.S., Medical Science, Korea University
Mar 2006 - Feb 2013 : B.S., Molecular Life Science, Hanyang University
- Research Interests
- Cancer target discovery and designing the therapeutics for immunotherapy.
Analysis of the genomic and transcriptomic data using statistics and machine-learning(deep learning) approaches.
Investigation of the association between cancer and aging.
Translational research on clinical outcome.
- Achievements
-
[ Journal Papers ]
Kang J, Lee JH, Cha H, An J, Kwon J, Lee S, Kim S, Baykan MY, Kim SY, An D, Kwon AY, An HJ, Lee SH, Choi JK, Park JE. Systematic dissection of tumor-normal single-cell ecosystems across a thousand tumors of 30 cancer types. Nature Communications. 2024 May 14;15(1):4067. doi: 10.1038/s41467-024-48310-4. PMID: 38744958; PMCID: PMC11094150.
Kwon J*, Kang J*, Jo A, Seo K, An D, Baykan MY, Lee JH, Kim N, Eum HH, Hwang S, Lee JM, Park WY, An HJ, Lee HO, Park JE, Choi JK. Single-cell mapping of combinatorial target antigens for CAR switches using logic gates. Nature Biotechnology. 2023 Feb 16. doi: 10.1038/s41587-023-01686-y. Epub ahead of print. PMID: 36797491. *Co-first
Kwon J*, Lee JH*, Lee YH, Lee J, Ahn JH, Kim SH, Kim SH, Kim TI, Yun KH, Park YS, Kim JE, Lee KS, Choi JK, Kim HS. Whole-Genome and Transcriptome Sequencing Identified NOTCH2 and HES1 as Potential Markers of Response to Imatinib in Desmoid Tumor (Aggressive Fibromatosis): A Phase II Trial Study. Cancer Research and Treatment. 2022 Oct;54(4):1240-1255. doi: 10.4143/crt.2021.1194. Epub 2022 Jan 17. PMID: 35038826; PMCID: PMC9582486. *Co-first
Lim SA, Kim J, Jeon S, Shin MH, Kwon J, Kim TJ, Im K, Han Y, Kwon W, Kim SW, Yee C, Kim SJ, Jang JY, Lee KM. Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients. Frontiers in Immunology. 2019 Apr 9;10:496. doi: 10.3389/fimmu.2019.00496. PMID: 31024520; PMCID: PMC6465515.
