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Youngwook KIM

Name
Youngwook KIM, Ph.D.
Faculty Appointment
(title, department)
Associate Professor,
Department of Cancer Biomedical Science
Area of Expertise
Cancer Genomics, Mitochondrial Biology, Functional Genomics
E-mail
youngwkim@ncc.re.kr
Work Experience
Samsung Genome Institute, Samsung Medical Center
SAIHST, Sungkyunkwan University
Educational Background
Seoul National University (B.S.) / Major: Molecular Biology, Minor: Physics
Sungkyunkwan University (Ph.D.) / Molecular and Cellular Biology
Research Interests
Cancer Genomics, Statistical analyses of big data,
Mitochondria and Cancer metabolism, Single cell biology
Achievements
1. Bak SH1. Gary DJ, Lee H, Sharma R, Lee JS, Kim Y, Cui ZY, Jia D, Bowman VD, Chipman PR, et al. Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: polyplexes vs micelleplexes. ACS Nano. (2011) 5(5):3493-505. (i.f. = 13.3) PMID: 21456626

2. Kim Y, Ko J, Cui Z, Abolhoda A, Ahn JS, Ou SH, Ahn MJ, Park K The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor Mol. Cancer Ther. (2012) Mar. 11(3):784-91. (i.f. = 5.6, cited more than 100 times) PMID:22228822

3. Jo SM*, Kim Y*, Jeong YS, Hee Oh Y, Park K, Kim HS. Rapid detection of exon 2-deleted AIMP2 mutation as a potential biomarker for lung cancer by molecular beacons. Biosens. Bioelectron. (2013) Aug. 46:142-9.
* equally contributing authors (i.f. = 7.5) PMID:23537880v 4. Kim Y, Hammerman P, Kim JG, Yoon J, Lee Y, Sun J, Wilkerson M, Pedamallu C, Cibulskis K, Yoo Y, Lawrence M, et al. Integrative and comparative genomic analysis of lung squamous cell carcinomas in East-Asians J. Clin. Oncol. (2014) Jan 10; 32(2):121-8. (i.f. = 24.0, cited more than 100 times) PMID: 24323028

5. Lee JY1, Kim JH, Bae KH, Oh MH, Kim Y, Kim JS, Park TG, Park K, Lee JH, Nam YS Low-density lipoprotein-mimicking nanoparticles for tumor-targeted theranostic applications. Small. (2015) Jan 14;11(2):222-31 (i.f. = 8.3) PMID: 25137631

6. Kim J*, Kim Y*, Kim J, Lee J, Bae K, Min J, Park T, Lee J, Nam Y, Park K Tumor-Targeted Delivery of Paclitaxel using low density lipoprotein-mimetic Solid Lipid Nanoparticles Mol. Pharm. (2015) Apr. 6; 12(4):1230-41. *equally contributing authors (i.f. = 4.3, ACS featured article)

7. Bak SH, Park H, Lee HY, Kim Y, Kim HL, Jung SH, Kim H, Kim J, Park K. Imaging genotyping of functional signaling pathways in lung squamous cell carcinoma using a radiomics approach Sci Rep. (2018) Feb 19; 8(1):3284. (i.f. = 4.3) PMID: 29459639

8. Cho S, Chae J, Shin H, Shin Y, Song H, Kim Y, Yoo B, Roh K, Cho S, Kil E, Byun H, Cho S, Park S, Lee S, Yeom C Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression Sci Rep. (2018) Jul 27; 8(1):11372 (i.f. = 4.3) PMID: 30054560

9. Yuan Y*, Ju Y*, Kim Y*, Li J, Wang Y, Yoon C, Yang Y, Martincorena I, Creighton C, Weinstein J, Xu Y, Han L, Kim H, Nakagawa H, Park K, Campbell P, Liang H Comprehensive molecular characterization of mitochondrial genomes in human cancers Nat.Genetics (2020) Feb 5. (Epub ahead of print) PMID: 32024997 * equally contributing authros (i.f. = 27.4)

10. Rheinbay E, Nielsen M, Abascal F, Tiao G, Hornshøj H, Hess J, Pedersen R, Feuerbach L, Sabarinathan R, Lin Z, Madsen T, Kim J, Mularoni L, Shuai S, Kim Y, Lehmann K, Johnson T, Kahraman T, Park K, Saksena G, Sieverling L, Sinnott-Armstrong N, Campbell P, Hobolth A, Kellis M, Lawrence M, Raphael B, Rubin M, Sander C, Stein L, Stuart J, Tsunoda T, Wheeler D, Johnson R, Reimand J, Gerstein M, Khurana E, López-Bigas N, Martincorena I, Pedersen J, Getz G Analyses of non-coidng somatic drivers in 2,658 cancer whole genomes Nature Feb 5. (Epub ahead of print) PMID: 32025015

11. Kim Y, Song S, Lee M, Swatloski T, Kang J, Ko Y, Park WY, Jeong H, Park K Integrative Genomic Analysis of Salivary Duct Carcinoma (submitted)