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Sung, Jee Young

Sung, Jee Young
Faculty Appointment
(title, department)
Research Assistant Professor,
Metastasis Branch, Division of Cancer Biology
Area of Expertise
Cell biology, Molecular biology, Mouse model for disease
Contact no
Work Experience
Post-Doctoral Associate 2003 –2007
Molecular & Cellular Neuroscience Laboratory
Rockefeller University, New York, USA
Research Professor 2008- 2009
System Biology, Yonsei University
Post-doctoral fellow
Center for Pediatric Oncology 2009- Present
National Cancer Center, Korea
Educational Background
Ewha Womans University 1997
B.S. in Biology
Ewha Womans University 1999
M.S. in Cell Biology
Yonsei University College of Medicine 2003
Ph.D in Neuroscience
Research Interests
Cancer metastasis, Circulating Tumor Cells, Osteosarcoma.
Fibronectin regulates anoikis resistance via cell aggregate formation Cancer Letters 2021.03(IF:7.3)

FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo Cancers 2021.01 (IF:6.63)

Anti-Tumor Effects of Sodium Meta-Arsenite in Glioblastoma Cells with Higher Akt Activities International Journal of Molecular Sciences, 2020-11, (IF:4.556)

Pygenic Acid A (PA) Sensitizes Metastatic Breast Cancer Cells to Anoikis and Inhibits Metastasis In Vivo International Journal of Molecular Sciences, 2020-11, (IF:4.556)

Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway Biomolecules, 2020-11 (IF:4.694)

Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling International Journal of Molecular Sciences (2020-10), (IF:4.556)

Suppressor of Variegation 3-9 Homolog 2, a Novel Binding Protein of Translationally Controlled Tumor Protein, Regulates Cancer Cell Proliferation Biomol Ther (2019-02), (IF:2.65)

C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle. Cells, (2019-02), (IF:5.2)

Upregulation of transforming growth factor-beta type I receptor by interferon consensus sequence-binding protein in osteosarcoma cells BBA-Molecular Cell Research, (2019-05) (IF:4.65)

FAM188B enhances cell survival via interaction with USP7 Cell Death and Disease (2018-05), (IF:5.6)

Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1b-Mediated Inflammatory Signaling through Phosphorylation of RCAN1 Frontier in Cellular Neurosciences (2017-05) (IF:4.555)

Regulation of Anoikis Resistance by NADPH Oxidase 4 and Epidermal Growth Factor Receptor British Journal of Cancer (2017-01), (IF:6.1)

Oncogenic Role of Rab Escort Protein 1 (REP1) through EGFR and STAT3 pathway Cell Death Dis. 2017-02 (IF:5.387)

Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells. Cell Death Disease. 2014-05, (IF:5.387)

Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis. Biochim Biophys Acta. 2014 -01, (IF:4.381)

An In Vivo C. elegans Model System for Screening EGFR-Inhibiting Anti-Cancer Drugs PLoS One. 2012-09, (IF: 4.2)

Anoikis resistance: An essential prerequisite for tumor metastasis Int J Cell Biol. 2012-12, Review

Dyrk1A negatively regulates actin cytoskeleton through threonine phosphorylation of N-WASP J Cell Sci. 2012 Jan 1, (IF:6.1)

Interferon consensus sequence binding protein-induced cell proliferation is mediated by TGF-β signaling and p38 MAPK activation. Lab Invest. 2011 -09, (IF: 4.6)

Induction of apoptosis by the ginsenoside Rh2 by internalization of lipid rafts and caveolae and inactivation of Akt Br J Pharmacol. 2010-06, (IF:5.2)

WAVE1 mediates mitochondrial distribution in dendrite spines Proc Natl Acad Sci U S A. 2008 -02 (IF:10.2)

The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A Proc Natl Acad Sci U S A. 2007-06 (IF: 10.2)

Alpha-synuclein overexpression reduces gap junctional intercellular communication in dopaminergic neuroblastoma cells Neurosci Lett. 2007-04 (IF:2.1)

Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation JBC 2006-11 (IF:5.2)

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology Nature. 2006-08 (IF:26.7)