교수진 소개 │ 교육 │ GCSP

교수진

교수진 소개

Sung, Jee Young

Name: Sung, Jee Young
Faculty Appointment (title, department): Research Assistant Professor,
Metastasis Branch, Division of Cancer Biology
Area of Expertise: Cell biology, Molecular biology, Mouse model for disease
Contact no: +82-31-920-2417
E-mail: sungjy@ncc.re.kr

Work Experience: Post-Doctoral Associate 2003 –2007
Molecular & Cellular Neuroscience Laboratory
Rockefeller University, New York, USA
Research Professor 2008- 2009
System Biology, Yonsei University
Post-doctoral fellow
Center for Pediatric Oncology 2009- Present
National Cancer Center, Korea
Educational Background: Ewha Womans University 1997
B.S. in Biology
Ewha Womans University 1999
M.S. in Cell Biology
Yonsei University College of Medicine 2003
Ph.D in Neuroscience
Research Interests: Cancer metastasis, Circulating Tumor Cells, Osteosarcoma.
Achievements: Fibronectin regulates anoikis resistance via cell aggregate formation Cancer Letters 2021.03(IF:7.3)

FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo Cancers 2021.01 (IF:6.63)

Anti-Tumor Effects of Sodium Meta-Arsenite in Glioblastoma Cells with Higher Akt Activities International Journal of Molecular Sciences, 2020-11, (IF:4.556)

Pygenic Acid A (PA) Sensitizes Metastatic Breast Cancer Cells to Anoikis and Inhibits Metastasis In Vivo International Journal of Molecular Sciences, 2020-11, (IF:4.556)

Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway Biomolecules, 2020-11 (IF:4.694)

Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling International Journal of Molecular Sciences (2020-10), (IF:4.556)

Suppressor of Variegation 3-9 Homolog 2, a Novel Binding Protein of Translationally Controlled Tumor Protein, Regulates Cancer Cell Proliferation Biomol Ther (2019-02), (IF:2.65)

C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle. Cells, (2019-02), (IF:5.2)

Upregulation of transforming growth factor-beta type I receptor by interferon consensus sequence-binding protein in osteosarcoma cells BBA-Molecular Cell Research, (2019-05) (IF:4.65)

FAM188B enhances cell survival via interaction with USP7 Cell Death and Disease (2018-05), (IF:5.6)

Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1b-Mediated Inflammatory Signaling through Phosphorylation of RCAN1 Frontier in Cellular Neurosciences (2017-05) (IF:4.555)

Regulation of Anoikis Resistance by NADPH Oxidase 4 and Epidermal Growth Factor Receptor British Journal of Cancer (2017-01), (IF:6.1)

Oncogenic Role of Rab Escort Protein 1 (REP1) through EGFR and STAT3 pathway Cell Death Dis. 2017-02 (IF:5.387)

Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells. Cell Death Disease. 2014-05, (IF:5.387)

Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis. Biochim Biophys Acta. 2014 -01, (IF:4.381)

An In Vivo C. elegans Model System for Screening EGFR-Inhibiting Anti-Cancer Drugs PLoS One. 2012-09, (IF: 4.2)

Anoikis resistance: An essential prerequisite for tumor metastasis Int J Cell Biol. 2012-12, Review

Dyrk1A negatively regulates actin cytoskeleton through threonine phosphorylation of N-WASP J Cell Sci. 2012 Jan 1, (IF:6.1)

Interferon consensus sequence binding protein-induced cell proliferation is mediated by TGF-β signaling and p38 MAPK activation. Lab Invest. 2011 -09, (IF: 4.6)

Induction of apoptosis by the ginsenoside Rh2 by internalization of lipid rafts and caveolae and inactivation of Akt Br J Pharmacol. 2010-06, (IF:5.2)

WAVE1 mediates mitochondrial distribution in dendrite spines Proc Natl Acad Sci U S A. 2008 -02 (IF:10.2)

The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A Proc Natl Acad Sci U S A. 2007-06 (IF: 10.2)

Alpha-synuclein overexpression reduces gap junctional intercellular communication in dopaminergic neuroblastoma cells Neurosci Lett. 2007-04 (IF:2.1)

Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation JBC 2006-11 (IF:5.2)

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology Nature. 2006-08 (IF:26.7)